Skip to Content
Menu

Grandma’s Chicken Casserole

  • Save Recipe
Inspiration awaits, let's get making!
  • Prep 10 min
  • Total 45 min
  • Servings 8
  • Save
  • Print
  • Pinterest
  • Facebook
  • Email
Ready to Make?
  • Save
  • Shop
  • Share
  • Keep Screen On

We all know how busy the week can get between work, school and activities—it’s a whirl! That’s when a great casserole really comes in handy. You can get a scrumptious dinner on the table, and spend some quality time with your family.

This recipe for Grandma’s Chicken Casserole is one of our fall staples, and the reason is simple: It’s made with cream of chicken soup, cheddar cheese and tender chicken, and then topped with buttery panko. It bakes up super creamy and crunchy. The ultimate comfort food!

For all that old-fashioned goodness, the chicken casserole really comes together with modern speed. Thanks to smart-shortcut ingredients like canned soup, shredded cheese and bread crumbs, you only need about 10 minutes of hands-on prep time to make it. What about the chicken? To save even more time and effort, pick up a rotisserie chicken at your local grocery store—you can eat it for dinner one night and then use the leftovers to make a casserole later in the week. Two dinners, done and dusted!

By Jessica Walker
Updated Aug 31, 2023
  • Save
  • Shop
  • Share
  • Keep Screen On

How should I serve grandma’s casserole?

We’d serve Grandma’s Chicken Casserole for a weeknight dinner with a side of green beans or a big green salad with lots of crunchy veggies. (You could also put a little hot sauce on the table—the casserole is great with a shake or two of Louisiana hot sauce.) This is also a casserole you’re going to want to take to potlucks: you’ll definitely go home with an empty dish!

Ingredients

  • 3 cups shredded or chopped cooked chicken
  • 2 cans (10.5 oz each) condensed cream of chicken soup
  • 2 cups shredded cheddar cheese (8 oz)
  • 3 cups Progresso™ plain panko crispy bread crumbs
  • 6 tablespoons butter, melted
Make With
Progresso Breadcrumbs

Steps

  • 1
    Heat oven to 350°F.
  • 2
    Evenly place chicken in bottom of ungreased 13x9-inch (3-quart) baking dish.
  • 3
    Spoon and evenly spread soup over chicken.
  • 4
    Evenly sprinkle cheese over soup.
  • 5
    In a medium bowl, combine bread crumbs and butter until well mixed.
  • 6
    Evenly sprinkle bread crumb mixture over cheese.
  • 7
    Bake for 30 to 35 minutes or until the cheese is melted, the bread crumbs are golden brown and the casserole is heated through.
  • 8
    Let stand 10 minutes before serving.

Tips from the Betty Crocker Kitchens

  • tip 1
    Grandma might not have used panko bread crumbs, but we love the texture they add to this recipe! They crisp up beautifully in the oven, so they’re nice and crunchy on your fork—the perfect contrast to all that creamy-dreamy chicken.
  • tip 2
    Leftover chicken casserole can be stored in an airtight container in the refrigerator up to 4 days. To reheat, bake at 350°F. in an oven-safe dish about 15 minutes or until thermometer inserted in center reaches 165°F.
  • tip 3
    Looking to make Grandma’s Chicken Casserole your own? Feel free to sub in your favorite flavors. For example, instead of panko bread crumbs, you could top your casserole with crispy French-fried onions. You can also have fun with the cheese: try a Colby-Monterey Jack cheese blend or nutty Gruyère instead of cheddar cheese.

Frequently Asked Questions

Why don't you grease the pan?

Between the cream of chicken soup and the cheddar cheese, there’s enough fat in the dish to keep it from sticking to the pan during baking.

What other meats can I use in Grandma’s Chicken Casserole?

Leftover roast turkey is a great substitute for chicken in this recipe—especially the day after Thanksgiving. It’s a one-to-one substitution, so you can just add three cups of the cooked meat when you toss together the other ingredients.

Nutrition

520 Calories, 29g Total Fat, 27g Protein, 37g Total Carbohydrate, 2g Sugars

Nutrition Facts

Serving Size: 1 Serving
Calories
520
Calories from Fat
260
Total Fat
29g
45%
Saturated Fat
14g
68%
Trans Fat
1g
Cholesterol
105mg
34%
Sodium
1060mg
44%
Potassium
170mg
5%
Total Carbohydrate
37g
12%
Dietary Fiber
0g
0%
Sugars
2g
Protein
27g
% Daily Value*:
Vitamin A
15%
15%
Vitamin C
0%
0%
Calcium
20%
20%
Iron
8%
8%
Exchanges:
1 Starch; 0 Fruit; 1 1/2 Other Carbohydrate; 0 Skim Milk; 0 Low-Fat Milk; 0 Milk; 0 Vegetable; 0 Very Lean Meat; 2 1/2 Lean Meat; 1 High-Fat Meat; 2 1/2 Fat;
Carbohydrate Choice
2 1/2
*Percent Daily Values are based on a 2,000 calorie diet.

More About This Recipe

© 2024 ®/TM General Mills All Rights Reserved
< div class="recipeContentBottom">