1Heat oven to 375°F. Spray 15x10x1-inch baking pan with cooking spray.
2In shallow dish, mix Bisquick mix, salt, paprika, chile powder and lemon-pepper seasoning. In another shallow dish, place evaporated milk. Dip fillets in milk, then coat with seasoned Bisquick mixture (discard any remaining mixture). Place fillets in baking dish. Spray tops of fillets with cooking spray to moisten.
3Bake uncovered 15 to 20 minutes or until fish flakes easily with fork. Meanwhile, in large bowl, mix all salsa ingredients. Let stand 10 to 15 minutes. Stir well; taste and adjust seasoning as needed.
4To serve, place fish on warm plates and top each fillet with 1/2 cup of salsa.