1Heat oven to 400°F. Grease 8-inch square pan with shortening or cooking spray.
2In medium bowl, stir together Bisquick mix, milk, egg, granulated sugar and 1 teaspoon pumpkin pie spice until well blended. Pour half of the batter into pan. Spread pumpkin pie mix over batter; pour remaining batter on top.
3In small bowl, mix all topping ingredients with fork until crumbly. Sprinkle over batter; lightly drag butter knife through topping to mix with top layer of batter.
4Bake 25 minutes or until toothpick inserted in center comes out clean. Serve warm or cool.