1Heat oven to 350°F. Spray 9x5-inch loaf pan with cooking spray.
2In large bowl, stir together Bisquick mix, cheese, Italian seasoning and pepperoni. Add milk, egg product and butter, stirring just until dry ingredients are moistened. Spoon batter into pan. Swirl pesto through batter with knife for marbled design.
3Bake 50 to 55 minutes or until toothpick inserted in center comes out clean. Cool 5 minutes. Remove from pan to cooling rack; cool completely before slicing.