1Heat the oven to 450°F. In 10-inch skillet, cook ground beef over medium-high heat 5 to 7 minutes, stirring frequently, until thoroughly cooked; drain. Stir in pizza sauce. Set aside.
2In large bowl, stir Bisquick mix, water and oil until dough forms (add additional tablespoon of water if needed). Place dough on surface sprinkled with Bisquick mix; roll in Bisquick mix to coat. Shape dough into a ball; knead about 5 times or until smooth.
3Divide dough in half. Press or roll each half into 12-inch round. On ungreased cookie sheet, place each dough round. Top half of each round with cheese and beef mixture. Fold the other half of each over filling; press with fork to seal.
4Bake 15 to 20 minutes or until golden brown. Remove from cookie sheets to cutting boards. Cool 5 minutes. Cut each calzone into 5 wedges.