1Heat oven to 325°F. In 5-quart Dutch oven or 13x9-inch (3-quart) glass baking dish, toss beef with flour. Add frozen vegetables.
2In large bowl, mix remaining ingredients. Pour over beef and vegetables; gently stir until mixed.
3Cover; bake 3 hours 30 minutes to 4 hours or until beef is tender. Remove bay leaves before serving.