I am a Memphis transplant to Chicago almost 30 years now and still miss the best BBQ that is everywhere in Memphis, BUT that being said, Smoque is a great addition to the Chicago BBQ scene. They do sell out from time to time and that means you know you are getting fresh 'cue everytime you go. Never really like brisket before (Texas BBQ) but tried it at Smoque and it is delicious. Their pulled pork is also tops and the offering of side dishes are nice.
It is easy to find, just south of Pulaski and Irving Park, right off the freeway. I like to go for lunch. Hope you will give it a try!
Another good one is Fat Willy's. Both have websites, Google them if you need more info.